- 1956 -
Founded as Toho Bussan Koeki, LTD. by Nikko Shoji,Ltd. investment.
Contracted with Permachem Corporation(Florida, USA),
started to produce and sell Permachem products in Japan and Southeast Asia.
- 1957 -
Research institute established in Tokyo,Kita-Ku.
Toho Bussan Koeki, LTD. renamed Permachem Asia, LTD. by contract with Permachem Corporation.
(Terminated contract with Permachem Corporation and became a stand-alone company after that.)
- 1958 -
Head office relocated to Tokyo Chuo-ku Nihonbashi Ningyocho and expanded microbial test facility.
- 1960 -
Yokohama Factory established. Research institute trensferred to the same place.
- 1972 -
Yokohama Factory renamed Yokohama Office.
- 1975 -
Torihama Factory established to improve productivity. Take a stake in Yokohama Kigyo, LTD.
- 1980 -
Head office relocated to Tokyo Chuo-ku Nihonbashi Horidomecho.
- 1983 -
Kikugawa Factory founded as medicine factory.
- 1989 -
Hokkaido branch office established in Tomakomai city to strengthen sales in Hokkaido district.
- 1992 -
R&D center established to reinforce of research, development and microbial test ability.
- 1994 -
Tokai branch office estalished in Kikugawa city to strengthen sales in Tokai district.
- 2004 -
Head office relocated in Nihonbashi Odenmacho.
- 2010 -
Head office relocated in current location.
- 2012 -
Kikugawa Factory 4th plant Established to expand supply API for generic drug.